SARS-CoV-2 viruses can hide from recognition by the immune system. However, the antiviral immune receptor RIG-I can be stimulated, which improves protection against lethal SARS-CoV-2 infections. Researchers led by Prof. Dr. Gunther Hartmann from the Institute of Clinical Chemistry and Clinical Pharmacology at the University Hospital Bonn, in cooperation with other members of the cluster of excellence ImmunoSensation2 at the University of Bonn, have shown this in mice. Also, the incidence of severe disease progression was observed to be significantly reduced. The study was published online in advance in the journal "Molecular Therapy - Nucleic Acids" and is now available in the final version.
Stress seems to have a negative effect on the learning of movements - at least in mice. This is the conclusion of a recent study at the University of Bonn. According to the study, the neurons of rodents lose some of their contacts with other neurons after stress. The animals also developed motor deficits. The results may be useful for earlier diagnosis and improved therapy of stress-related diseases such as depression. They also document that stress leaves traces in the brain - possibly permanent ones. The study appeared in the journal Translational Psychiatry.
Artificial intelligence (AI) already plays a very important role in medical research, diagnostics and therapy. The pursuit of individualized, targeted and thus as gentle as possible therapy requires a fast and precise evaluation of large amounts of data. The Department of Diagnostic and Interventional Radiology at the University Hospital Bonn (UKB) is intensively involved in the use of artificial intelligence methods. Under the leadership of Prof. Dr. Ulrike Attenberger, Director of the Clinic for Diagnostic and Interventional Radiology, the 10th Young Investigators Academy of the German Research Foundation (DFG) will be held in Bonn in April on the topic of artificial intelligence in radiology.
The University of Bonn condemns the invasion of Russian troops and expresses its solidarity with the people in Ukraine. In solidarity with German academic institutions, it is suspending all cooperation with Russian partner institutions until further notice.
Rayk Behrendt took over the W2 professorship for Nucleic Acid Immunity with tenure track as of March 1, 2022. The professorship is associated with the Institute of Clinical Chemistry and Clinical Pharmacology of the Medical Faculty Bonn.
Multiple sclerosis sufferers often complain of more severe disease symptoms after consuming dairy products. Researchers at the Universities of Bonn and Erlangen-Nuremberg have now found a possible cause for this. According to the study, a protein in cow's milk can trigger inflammation that targets the "insulating layer" around nerve cells. The study was able to demonstrate this link in mice, but also found evidence of a similar mechanism in humans. The researchers therefore recommend that certain groups of sufferers avoid dairy products. The study has now been published in the journal PNAS.
The University of Bonn has again recruited high-ranking personalities. Prof. Dr. Carmen Ruiz de Almodóvar and Prof. Dr. Martin Keßler are now taking up so-called Schlegel Professorships, which are financed by excellence funds. The internationally recognized researchers will open up new fields of research at the University of Bonn and provide important impulses in the life sciences and Protestant theology.
How can a customized chemotherapy be found for cancer, for example? Machine learning methods can help with this and also improve patient treatment for other diseases. The start-up project aimed analytics at the University of Bonn has developed a modular analysis system that precisely groups patients on the basis of medical Big Data. The team of Dr. Kevin Baßler, Dr. Patrick Günther and Karsten Waltemathe has now received a coveted EXIST start-up grant of 130,000 euros from the German Federal Ministry for Economic Affairs and Energy for one year.