Three University of Bonn researchers have been awarded a Proof of Concept Grant by the European Research Council (ERC). Neuroscientist Professor Dominik Bach, chemist Assistant Professor Ala Bunescu and radiologist Professor Philipp Vollmuth (from the University Hospital Bonn) are each receiving €150,000 over a period of 18 months. This program helps researchers to take findings from their work and turn them into commercial products or services.

For the immune system to effectively combat pathogens, antibody responses must be precisely controlled. So-called follicular regulatory T cells (Tfr cells) play a key role in this process by limiting excessive immune responses and helping to maintain immune tolerance. Researchers at the University Hospital Bonn (UKB) and the University of Bonn have now developed a robust laboratory method that allows Tfr cells to be generated from precursor cells and studied in a targeted manner. The results were recently published in the journal Cellular & Molecular Immunology.

Every time we move through a familiar environment, the hippocampus consults an internal map, a detailed spatial representation that is built up through repeated experience. But what happens when something unexpected occurs on a well-known route? Researchers at the University Hospital Bonn (UKB) and the University of Bonn were able to demonstrate in a mouse model that the brain does not redraw its maps from scratch. Instead, it annotates them: preserving the underlying spatial layout while overlaying new information on top of the existing map. Their findings have now been published in the journal PNAS.

The Code of Conduct serves as a fundamental guide for teaching, studying, and working at the Faculty of Medicine at the Rheinische Friedrich-Wilhelms University of Bonn. It is intended to provide a sense of security in our interactions for faculty, students, and staff of diverse nationalities, backgrounds, and religious affiliations, and to foster a trusting atmosphere for learning, studying, and working.

The PearNet project is developing special wearables—body-worn electronic devices—that give epilepsy patients advance warning of seizures and monitor and record them when they happen. The brainchild of researchers from the University Hospital Bonn and University of Bonn, it has now secured some €2.7 million in funding over three years via the GO-Bio next program run by the Federal Ministry of Research, Technology and Space (BMFTR). The money will go toward making further preparations for spinning off the project so that its set of wearables can be launched on the biotechnology market.

People who want to do something for their health these days often turn to Instagram, TikTok, and other social media platforms for information. But what’s really behind the posts and trends shared by health influencers? On May 13, the Cluster of Excellence ImmunoSensation3 at the University of Bonn invited the public to join five professors for dinner to explore this question. In a relaxed atmosphere, social media posts on health and the immune system were presented, discussed by the approximately 40 participants, and analyzed together with the experts. The launch of this new format took place at John Barleycorn as part of Bonn’s “May of Science.”

The German Research Foundation (Deutsche Forschungsgemeinschaft, DFG) has announced that a new Collaborative Research Center (CRC) is to be set up at the University of Bonn: the “FoodDiverse” collaborative project, which is studying the diversification of food systems. The University will also be involved in a new CRC/Transregio (CRC-TRR) looking at narratives from pre-modern times and various cultural contexts, while two existing CRC-TRRs have been extended for another funding period. TRRs are projects that are implemented by several universities working together.

The loss of interest or pleasure in normally enjoyable activities, which is experienced in everyday life and can be very distressing, is a core symptom of major depression. However, it has remained unclear exactly how anhedonia, also known as a pleasure deficit, manifests itself. Researchers at the University Hospital Bonn (UKB), the University of Bonn, and the University Hospital Tübingen have found that people with depression do not perceive food as less rewarding when they actually consume it. The differences compared to people without depression emerge during anticipation: how much they want something before they receive it. This reduced desire is also linked to the clinical severity of anhedonia. The study’s findings have now been published in the journal “Cell Reports Medicine.”