Strong Showing for the University of Bonn

The University of Bonn did very well in the QS World University rankings released yesterday, being amongst the top 100 worldwide in roughly a third of the ranked Subjects. Mathematics is again our highest-ranking subject (41st internationally, 1st in Germany).

Pint of Science - Call for Scientists

The 6th Pint of Science invites all interested scientists to participate.

New findings on the immune system

T follicular helper cells (Tfh) are essential for strong antibody-mediated reactions of our immune system during infections and vaccinations. However, if they get out of control, this can cause diseases such as autoimmunity, allergies or cancer. Researchers from the University Hospital Bonn (UKB) and the Cluster of Excellence ImmunoSensation2 at the University of Bonn investigated the underlying mechanisms of Tfh cell development in a mouse model and thus decoded their internal networking. They hope that this will lead to new strategies for the development of highly effective vaccines and new therapies to combat various diseases. The results have now been published in the renowned journal "Science Immunology".
 
 

Long-term memory and lack of mental images

When people lack visual imagination, this is known as aphantasia. Researchers from the University Hospital Bonn (UKB), the University of Bonn and the German Center for Neurodegenerative Diseases (DZNE) investigated how the lack of mental imagery affects long-term memory. They were able to show that changes in two important brain regions, the hippocampus and the occipital lobe, as well as their interaction, have an influence on the impaired recall of personal memories in aphantasia. The study results, which advance the understanding of autobiographical memory, have now been published online by the journal "eLife".

False alarm of the immune system during muscle disease

Researchers at the University Hospitals of Dresden and Bonn of the DFG Transregio 237 and from the Cluster of Excellence ImmunoSensation2 at the University of Bonn have made progress clarifying why patients with myotonic dystrophy 2 have a higher tendency to develop autoimmune diseases. Their goal is to understand the development of the disease, and their research has provided new, potential therapeutic targets. The results of the study have now been published in the renowned journal "Nature Communications".
 
 

Artificial intelligence recognizes patterns in behaviour

Researchers from Carnegie Mellon University, the University Hospital Bonn and the University of Bonn have created an open-source platform known as A-SOiD that can learn and predict user-defined behaviors, just from video. The results of the study have now been published in the journal "Nature Methods".

Zebrafish Navigate to Find Their Comfortable Temperature

Zebrafish are smaller than your little finger, with a brain no more than half the size of a pinhead. Yet these animals possess an efficient navigation system that enables them to find their way back to spots in the water where the temperature suits them. This has been revealed in a recent study by the University of Bonn and University Hospital Bonn together with the Technical University of Munich (TUM), whose findings have been published in the journal “Current Biology.”

News on drug-induced skin swelling

Angioedema is a rare but potentially life-threatening adverse reaction to ACE inhibitors. In a joint analysis of eight European study collectives, researchers from the University Hospital Bonn (UKB), the University of Bonn and the Federal Institute for Drugs and Medical Devices (BfArM) for the first time conducted a genome-wide association study (GWAS) with more than 1,000 affected individuals. They identified a total of three risk loci in the genome. These included a new locus that had not previously been associated with the risk of ACE inhibitor-induced angioedema. The results of the study have now been published in the "Journal of Allergy and Clinical Immunology".
 
 

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