Covid-19: New energy for flagging immune cells

In severe Covid-19 patients, the metabolism produces insufficient amounts of certain energy-rich compounds called ketone bodies. However, these energy carriers are needed by two important cell types in the immune system in order to fight the virus effectively. Perhaps this finding explains why some people fall ill so much more severely than others. A study led by the University of Bonn and the University Hospital Bonn at least points in this direction. The results have now been published in the journal Nature. They also give hope for new therapies.

Pitch Contest of the Medical Faculty Bonn

Are you excited about the possibility that your research could make a difference in the world?. We'd like to help you achieve that with awards totaling EUR 60.000! All you have to do is apply and present your idea at the first ever Bonn Medical Pitch Contest on September 15, 2022.

Sperm are masters of tetris packing

During sperm production, an enormous amount of DNA has to be packed into a very small space without breaking anything. A central role is played by certain proteins around which the DNA thread is wrapped - the protamines. A recent study by the University of Bonn provides new insights into this important mechanism. The results have been published in the journal PLoS Genetics.

Molecule boosts fat burning

A study led by the University of Bonn and the University Hospital Bonn has identified a molecule - the purine inosine - that boosts fat burning in brown adipocytes. The mechanism was discovered in mice, but probably exists in humans as well: If a transporter for inosine is less active, the mice remain significantly leaner despite a high-fat diet. The study, which also involved researchers from the University of Leipzig and the University Medical Center Hamburg-Eppendorf, has now been published in the journal Nature.
 

NeurotechEU: Board of Rectors Meeting in Romania

NeurotechEU, the European University of Brain and Technology, has invited its members to attend its semi-annual Board of Rectors meeting at Iuliu Hațieganu Medical and Pharmaceutical University in Cluj-Napoca, Romania. In May a delegation from the University of Bonn Rectorate attended this meeting of the top governance board of the consortium to which the former is a member, called to inaugurate the second project phase.

Researchers from the Universities of Bonn and Cologne observe the danger sensor NLRP3

Redness, swelling, pain - these are signs of inflammation. It serves to protect the body from pathogens or foreign substances. Researchers from the Universities of Bonn and Cologne were able to show that inflammatory reactions of an important sensor protein proceed in a specific spatial direction. This finding has the potential to conceivably stop inflammation at the "growing end", and thus bring chronic inflammatory diseases to a halt. The study has now been published in the journal "Science Advances".

Honoring Outstanding and Dedicated Early-Career Researchers

The Universitätsgesellschaft Bonn (UGB) presented its prestigious prizes for superlative doctoral theses and its Initiative Award for student involvement during its spring matinée. The ceremony returned to being held in person in the Arithmeum.

Enzyme prevents brain activity from getting out of control

The brain has the ability to modify the contacts between neurons. Among other things, that is how it prevents brain activity from getting out of control. Researchers from the University Hospital Bonn, together with a team from Australia, have identified a mechanism that plays an important role in this. In cultured cells, this mechanism alters the synaptic coupling of neurons and thus stimulus transmission and processing. If it is disrupted, diseases such as epilepsy, schizophrenia or autism may be the result. The findings are published in the journal Cell Reports.

Wird geladen