Core Facility Translational Proteomics

We offer state-of-the-art mass spectrometry-based proteomics analyses of clinical sample cohorts, including biofluids, isolated cells, and tissue.

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Staff

Staff members of the core facility. Who supports scientific, answers technical questions, and performs measurements or statistical analyses.

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Methods

Offered sample preparation methods for clinical samples including isolated cells, tissue, and biofluids.

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Equipment

Main instrumentation for automated sample preparation and liquid chromatography-mass spectrometry measurements.

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FAQ

Answers to frequently asked questions about the core facility services.

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Consulting

Are you interested in our services? Please get in touch with the relevant contact person.

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Acknowledgement

You would like to publish your results but do not know how to take the support of the Core Facility into account? Here you will find detailed instructions.

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Publications

2024

Hawwari, Ibrahim; Rossnagel, Lukas; Rosero, Nathalia; Maasewerd, Salie; Vasconcelos, Matilde B.; Jentzsch, Marius et al. (2024): Platelet transcription factors license the pro-inflammatory cytokine response of human monocytes. In EMBO molecular medicine 16 (8), pp. 1901–1929. DOI: 10.1038/s44321-024-00093-3 .
Lea Seep; Stephan Grein; Iva Splichalova; Danli Ran; Mickel Mikhael; Staffan Hildebrand et al.: From Planning Stage Towards FAIR Data: A Practical Metadatasheet For Biomedical Scientists.
Wilms, Gerrit; Schofield, Kevin; Maddern, Shayna; Foley, Christopher; Shaw, Yeng; Smith, Breland et al. (2024): Discovery and Functional Characterization of a Potent, Selective, and Metabolically Stable PROTAC of the Protein Kinases DYRK1A and DYRK1B. In Journal of medicinal chemistry 67 (19), pp. 17259–17289. DOI: 10.1021/acs.jmedchem.4c01130 .

2023

Pruenster, Monika; Immler, Roland; Roth, Jonas; Kuchler, Tim; Bromberger, Thomas; Napoli, Matteo et al. (2023): E-selectin-mediated rapid NLRP3 inflammasome activation regulates S100A8/S100A9 release from neutrophils via transient gasdermin D pore formation. In Nat Immunol 24 (12), pp. 2021–2031. DOI: 10.1038/s41590-023-01656-1 .