Too much fat can be unhealthy: how fat cells, so-called adipocytes, develop, is crucial for the function of the fat tissue. That is why a team led by researchers from the University Hospital Bonn (UKB) and the University of Bonn investigated the influence of primary cilia dysfunction on adipocyte precursor cells in a mouse model. They found that overactivation of the Hedgehog signaling pathway causes abnormal development into connective tissue-like cells instead of white fat cells. Their findings have now been published in The EMBO Journal.

Emergencies, night shifts, high-pressure decision-making ... it takes more than specialized knowledge to work in medicine. That’s why the University of Bonn Faculty of Medicine offers courses specifically designed to help students become more mentally resilient, in cooperation with Jung-Stilling Siegen Hospital—a protestant social services clinic. Extreme athlete Joey Kelly returned as one of this year’s special course participants at University Hospital Bonn (UKB) and in Siegen, who did a night hike with outdoor sleeping together with students. 

A research team from the University Hospital Bonn (UKB), the University of Bonn, and the Medical Center – University of Freiburg has gained new insights into the brain processes involved in encoding and retrieving new memory content. The study is based on measurements of individual nerve cells in people with epilepsy and shows how they follow an internal rhythm. The work has now been published in the journal Nature Communications.

Artificial intelligence (AI) is designed to make our health system even more efficient. Yet cyberattacks are capable not only of jeopardizing patient safety but also impairing medical devices and hindering the work of emergency responders. With the “SecureNeuroAI” project, researchers from the University of Bonn, University Hospital Bonn and FIZ Karlsruhe – the Leibniz Institute for Information Infrastructure are aiming to develop secure, AI-powered methods for detecting medical emergencies in real time using the example of epileptic seizures, although their findings should be applicable to many other areas. The Federal Ministry of Research, Technology and Space (BMFTR) is providing almost €2.5 million in funding over a three-year period.

A current study by the German Familial Colorectal Cancer Consortium is looking at the question of which people with Lynch syndrome are at an increased risk of developing a second colorectal cancer. Researchers from the University Hospital Bonn (UKB), the University of Bonn and the University of Leipzig have now published their findings in the journal "Clinical Gastroenterology and Hepatology".

Asthma medications often lose their effectiveness over time, and do not prevent the bronchial tissue from thickening. Researchers at Ruhr University Bochum, the University of Bonn, and Bonn University Hospital, have successfully tested a plant-based agent that combats this dreaded remodeling process. Derived from the coralberry Ardisia crenata, the agent inhibits a specific protein, thus ensuring that less collagen accumulates in the bronchial tissue. Less mucus is produced and secreted as well. The researchers report their findings in the journal Molecular Therapy.

The University of Bonn has awarded teaching prizes to 14 teaching staff in recognition of their outstanding work. The prize recipients were chosen by students themselves. Professor Klaus Sandmann, Vice Rector for Teaching, Learning and University Development presented the prize certificates at a ceremony on the Hofgarten lawn in Bonn as part of the Universitätsfest attended by over 7,000 people.

Research is not an end in itself. Ultimately, it must have an impact on society, politics, culture or the economy for its purpose to fully unfold. And that is what the UGB Transfer Prize created by Universitätsgesellschaft Bonn (UGB) is all about. The 10,000-euro Prize is awarded in recognition of projects through which University of Bonn staff and students effectively transfer knowledge in innovative yet practical ways so as to visibly benefit society at large.