Zeiss LSM980 (Airyscan 2)
The Zeiss LSM 980 with Airyscan 2 is a state-of-the-art confocal laser scanning microscope designed for cutting-edge imaging in biomedical and life sciences research. Featuring the advanced Airyscan 2 detector, the system delivers super-resolution imaging beyond the diffraction limit while maintaining high sensitivity and speed. Its unique multiplexed detection enables fast, gentle imaging of live samples with enhanced resolution and signal-to-noise ratio. The LSM 980 supports a wide spectral range, seamless multi-channel acquisition, and precise Z-stack and 3D imaging, making it ideal for complex, dynamic biological systems. Combined with intuitive ZEN software and seamless integration of environmental control and automation, the LSM 980 provides unparalleled flexibility and performance for both fixed and live-cell imaging.
Funding information:
Deutsche Forschungsgemeinschaft (DFG, German Research Foundation) – Projektnummer 534092360 (see further information for acknowledgment)
Objectives:
| Mag. | Type | NA | Immersion | WD (mm) | Coverslip (µm) | Product number |
| 2.5x | EC Plan-NEOFLUAR | 0.085 | dry | 8.8 | 0.17 | 420320-9902-000 |
| 10x | PlanApochromat | 0.45 | dry | 2.0 | 0.17 | 420640-9900-000 |
| 20x | PlanApochromat | 0.8 | dry | 0.55 | 0.17 | 420650-9903-000 |
| 40x | LD LCI PApo FCS | 1.2 corr | water | 0.4 | 0.15 - 0.19 | 420862-9970-713 |
| 63x | C PApo DIC UV-IR | 1.40 | oil | 0.14 | 0.17 | 421782-9900-799 |
Laser Lines:
405 nm
445 nm
488 nm
514 nm
561 nm
639 nm
Detectors / Cameras:
Spectral detector (32 GaAsP + 2 MA-PMT)
Airyscan 2 detector (32 GaAsP)
Transmitted light detector (T-PMT 2)
Axiocam 807 mono
Accessories:
Dark environmental chamber
CO2-incubation
AI Sample Finder
Definite Focus 3
Software:
Zeiss Zen Blue Software
Modules: Airyscan Multiplex Plus, Airyscan Joint Deconvolution, LSM plus, Correlative Array Tomography (CAT), Spectral RICS, FCS/FCCS, Dynamics Profiler, Smart Acquisition
Funding
Deutsche Forschungsgemainschaft (DFG, German Research Foundation) – Projektnummer 534092360
The Core Facilities thank the German Research Foundation for continuous support.
